Computed Radiography ImageCIOD
CT ImageCIOD
MR ImageCIOD
Nuclear Medicine ImageCIOD
Ultrasound ImageCIOD
Ultrasound Multi-frame ImageCIOD
Secondary Capture ImageCIOD
Multi-frame Single Bit Secondary Capture ImageCIOD
Multi-frame Grayscale Byte Secondary Capture ImageCIOD
Multi-frame Grayscale Word Secondary Capture ImageCIOD
Multi-frame True Color Secondary Capture ImageCIOD
X-Ray Angiographic ImageCIOD
X-Ray Radiofluoroscopic ImageCIOD
RT ImageCIOD
RT DoseCIOD
RT Structure SetCIOD
RT PlanCIOD
Positron Emission Tomography ImageCIOD
Digital X-Ray ImageCIOD
Digital Mammography X-Ray ImageCIOD
Digital Intra-Oral X-Ray ImageCIOD
RT Beams Treatment RecordCIOD
RT Brachy Treatment RecordCIOD
RT Treatment Summary RecordCIOD
VL Endoscopic ImageCIOD
VL Microscopic ImageCIOD
VL Slide-Coordinates Microscopic ImageCIOD
VL Photographic ImageCIOD
Video Endoscopic ImageCIOD
Video Microscopic ImageCIOD
Video Photographic ImageCIOD
VL Whole Slide Microscopy ImageCIOD
Real-Time Video Endoscopic ImageCIOD
Real-Time Video Photographic ImageCIOD
Dermoscopic Photography ImageCIOD
Grayscale Softcopy Presentation StateCIOD
Color Softcopy Presentation StateCIOD
Pseudo-Color Softcopy Presentation StateCIOD
Blending Softcopy Presentation StateCIOD
Basic Structured DisplayCIOD
XA/XRF Grayscale Softcopy Presentation StateCIOD
Advanced Blending Presentation StateCIOD
Variable Modality LUT Softcopy Presentation StateCIOD
Basic Voice Audio WaveformCIOD
12-Lead ECGCIOD
General ECGCIOD
Ambulatory ECGCIOD
Hemodynamic WaveformCIOD
Basic Cardiac Electrophysiology WaveformCIOD
Arterial Pulse WaveformCIOD
Respiratory WaveformCIOD
General Audio WaveformCIOD
Real-Time Audio WaveformCIOD
Routine Scalp ElectroencephalogramCIOD
ElectromyogramCIOD
ElectrooculogramCIOD
Sleep ElectroencephalogramCIOD
Multi-channel Respiratory WaveformCIOD
Body Position WaveformCIOD
General 32-bit ECGCIOD
Basic Text SRCIOD
Enhanced SRCIOD
Comprehensive SRCIOD
Key Object Selection DocumentCIOD
Mammography CAD SRCIOD
Chest CAD SRCIOD
Procedure LogCIOD
X-Ray Radiation Dose SRCIOD
Spectacle Prescription ReportCIOD
Colon CAD SRCIOD
Macular Grid Thickness and Volume ReportCIOD
Implantation Plan SR DocumentCIOD
Comprehensive 3D SRCIOD
Radiopharmaceutical Radiation Dose SRCIOD
Extensible SRCIOD
Acquisition Context SRCIOD
Simplified Adult Echo SRCIOD
Patient Radiation Dose SRCIOD
Planned Imaging Agent Administration SRCIOD
Performed Imaging Agent Administration SRCIOD
Rendition Selection DocumentCIOD
Enhanced X-Ray Radiation Dose SRCIOD
Enhanced MR ImageCIOD
MR SpectroscopyCIOD
Enhanced MR Color ImageCIOD
Raw DataCIOD
Enhanced CT ImageCIOD
Spatial RegistrationCIOD
Deformable Spatial RegistrationCIOD
Spatial FiducialsCIOD
Ophthalmic Photography 8 Bit ImageCIOD
Ophthalmic Photography 16 Bit ImageCIOD
Stereometric RelationshipCIOD
Hanging ProtocolCIOD
Encapsulated PDFCIOD
Encapsulated CDACIOD
Real World Value MappingCIOD
Enhanced XA ImageCIOD
Enhanced XRF ImageCIOD
RT Ion PlanCIOD
RT Ion Beams Treatment RecordCIOD
SegmentationCIOD
Ophthalmic Tomography ImageCIOD
X-Ray 3D Angiographic ImageCIOD
X-Ray 3D Craniofacial ImageCIOD
Breast Tomosynthesis ImageCIOD
Enhanced PET ImageCIOD
Surface SegmentationCIOD
Color PaletteCIOD
Enhanced US VolumeCIOD
Lensometry MeasurementsCIOD
Autorefraction MeasurementsCIOD
Keratometry MeasurementsCIOD
Subjective Refraction MeasurementsCIOD
Visual Acuity MeasurementsCIOD
Ophthalmic Axial MeasurementsCIOD
Intraocular Lens CalculationsCIOD
Generic Implant TemplateCIOD
Implant Assembly TemplateCIOD
Implant Template GroupCIOD
RT Beams Delivery InstructionCIOD
Ophthalmic Visual Field Static Perimetry MeasurementsCIOD
Intravascular Optical Coherence Tomography ImageCIOD
Ophthalmic Thickness MapCIOD
Surface Scan MeshCIOD
Surface Scan Point CloudCIOD
Legacy Converted Enhanced CT ImageCIOD
Legacy Converted Enhanced MR ImageCIOD
Legacy Converted Enhanced PET ImageCIOD
Corneal Topography MapCIOD
PatientMModule - Patient
(0008,1120) Referenced Patient Sequence3Sequence
(0010,0010) Patient's Name2Person Name
(0010,0020) Patient ID2Long String
(0010,0021) Issuer of Patient ID3Long String
(0010,0022) Type of Patient ID3Code String
(0010,0024) Issuer of Patient ID Qualifiers Sequence3Sequence
(0010,0026) Source Patient Group Identification Sequence3Sequence
(0010,0027) Group of Patients Identification Sequence3Sequence
(0010,0030) Patient's Birth Date2Date
(0010,0032) Patient's Birth Time3Time
(0010,0033) Patient's Birth Date in Alternative Calendar3Long String
(0010,0034) Patient's Death Date in Alternative Calendar3Long String
(0010,0035) Patient's Alternative Calendar1CCode String
(0010,0040) Patient's Sex2Code String
(0010,0200) Quality Control Subject3Code String
(0010,0212) Strain Description3Unlimited Characters
(0010,0213) Strain Nomenclature3Long String
(0010,0216) Strain Stock Sequence3Sequence
(0010,0218) Strain Additional Information3Unlimited Text
(0010,0219) Strain Code Sequence3Sequence
(0010,0221) Genetic Modifications Sequence3Sequence
(0010,0222) Genetic Modifications Description1Unlimited Characters
(0010,0223) Genetic Modifications Nomenclature1Long String
(0010,0229) Genetic Modifications Code Sequence3Sequence
(0010,1001) Other Patient Names3Person Name
(0010,1002) Other Patient IDs Sequence3Sequence
(0010,1100) Referenced Patient Photo Sequence3Sequence
(0010,2160) Ethnic Group3Short String
(0010,2201) Patient Species Description1CLong String
(0010,2202) Patient Species Code Sequence1CSequence
(0010,2292) Patient Breed Description2CLong String
(0010,2293) Patient Breed Code Sequence2CSequence
(0010,2294) Breed Registration Sequence2CSequence
(0010,2297) Responsible Person2CPerson Name
(0010,2298) Responsible Person Role1CCode String
(0010,2299) Responsible Organization2CLong String
(0010,4000) Patient Comments3Long Text
(0012,0062) Patient Identity Removed3Code String
(0012,0063) De-identification Method1CLong String
(0012,0064) De-identification Method Code Sequence1CSequence
Clinical Trial SubjectUModule - Patient
General StudyMModule - Study
Patient StudyUModule - Study
Clinical Trial StudyUModule - Study
General SeriesMModule - Series
Clinical Trial SeriesUModule - Series
Corneal Topography Map SeriesMModule - Series
General EquipmentMModule - Equipment
Enhanced General EquipmentMModule - Equipment
Frame of ReferenceMModule - Frame of Reference
General AcquisitionMModule - Acquisition
General ImageMModule - Image
General ReferenceUModule - Image
Image PixelMModule - Image
Palette Color Lookup TableMModule - Image
Corneal Topography Map ImageMModule - Image
Corneal Topography Map AnalysisMModule - Image
Ophthalmic Photography Acquisition ParametersMModule - Image
Acquisition ContextMModule - Image
ICC ProfileUModule - Image
SOP CommonMModule - Image
Breast Projection X-Ray ImageCIOD
Parametric MapCIOD
Wide Field Ophthalmic Photography Stereographic Projection ImageCIOD
Wide Field Ophthalmic Photography 3D Coordinates ImageCIOD
Tractography ResultsCIOD
RT Brachy Application Setup Delivery InstructionCIOD
Planar MPR Volumetric Presentation StateCIOD
Volume Rendering Volumetric Presentation StateCIOD
Content Assessment ResultsCIOD
CT Performed Procedure ProtocolCIOD
CT Defined Procedure ProtocolCIOD
Protocol ApprovalCIOD
XA Performed Procedure ProtocolCIOD
XA Defined Procedure ProtocolCIOD
Ophthalmic Optical Coherence Tomography En Face ImageCIOD
Ophthalmic Optical Coherence Tomography B-scan Volume AnalysisCIOD
Encapsulated STLCIOD
Encapsulated OBJCIOD
Encapsulated MTLCIOD
RT Physician IntentCIOD
RT Segment AnnotationCIOD
RT Radiation SetCIOD
C-Arm Photon-Electron RadiationCIOD
Tomotherapeutic RadiationCIOD
Robotic-Arm RadiationCIOD
RT Radiation Record SetCIOD
RT Radiation Salvage RecordCIOD
C-Arm Photon-Electron Radiation RecordCIOD
Tomotherapeutic Radiation RecordCIOD
Robotic-Arm Radiation RecordCIOD
RT Radiation Set Delivery InstructionCIOD
RT Treatment PreparationCIOD
Enhanced RT ImageCIOD
Enhanced Continuous RT ImageCIOD
RT Patient Position Acquisition InstructionCIOD
Microscopy Bulk Simple AnnotationsCIOD
InventoryCIOD
Photoacoustic ImageCIOD
Confocal Microscopy ImageCIOD
Confocal Microscopy Tiled Pyramidal ImageCIOD
Basic DirectoryCIOD

Built with by Innolitics, a team of medical imaging software developers.

Data synced with official DICOM standard on 18 April 2024. The DICOM Standard is under continuous maintenance, and the current official version is available at http://www.dicomstandard.org/current/. DICOM Parts 3, 4, and 6, © NEMA. Please note that the most recent PDF version of the standard is the official reference, and should checked when making technical decisions.

Genetic Modifications Sequence Attribute

Tag(0010,0221)
TypeOptional (3)
KeywordGeneticModificationsSequence
Value Multiplicity1
Value RepresentationSequence (SQ)

The genetic modifications of the Patient.

One or more Items are permitted in this Sequence.

See Section C.7.1.1.1.4.

Section C.7.1.1.1.4

C.7.1.1.1.4 Patient Strain and Genetic Modifications

The strain of a non-human organism (group of non-human organisms that is genetically uniform), if known, may be encoded in Strain Description (0010,0212). The nomenclature used may be encoded in Strain Nomenclature (0010,0213). A precoordinated code identifying the strain may be encoded in Strain Code Sequence (0010,0219).

Defined Terms for Strain Nomenclature (0010,0213) and Genetic Modifications Nomenclature (0010,0223):

MGI_2013

International Committee on Standardized Genetic Nomenclature for Mice, Rat Genome and Nomenclature Committee. MGI-Guidelines for Nomenclature of Mouse and Rat Strains. 2013/10. Available from: http://www.informatics.jax.org/mgihome/nomen/strains.shtml

Note

  • A pair of text and nomenclature Attributes are used, since standard nomenclatures typically define values that are constructed from multiple components, and do not distinguish between value and meaning. These are distinct from the precoordinated codes used in Strain Code Sequence (0010,0219).

  • Some strain and genetic modification nomenclatures make use of superscripts. To encode these superscripts consistently in an unformatted string, the convention of enclosing the superscript text in "<" and ">" pairs may be used. E.g., "D2.B6-Ahrb-1/J" would be encoded as "D2.B6-Ahr<b-1>/J".

  • Relevant information that is not encoded in the formal description of the strain (i.e., not defined in the nomenclature used), such as the number of transgenes, may be encoded as plain text in Strain Additional Information (0010,0218).

The strain of a non-human organism may be more specifically identified by the Attributes within Strain Stock Sequence (0010,0216).

Note

  • The MGI-Guidelines for Nomenclature of Mouse and Rat Strains recommends the use of the laboratory codes assigned by the Institute of Laboratory Animal Research (ILAR). See the International Laboratory Code Registry (ILCR) http://dels.nas.edu/global/ilar/lab-codes.

  • Because allele names are closely tied to gene names/symbols it is necessary to have a unique and permanent code for any allele that is part of a genotype of interest. For mice, MGI is the authoritative source of the nomenclature for genes and alleles and maintains unique, permanent codes for these entities. The MGI provides a report of all precoordinated MGI codes that are assigned to specific strains at http://www.informatics.jax.org/downloads/reports/MGI_Strain.rpt. These may be used in Strain Code Sequence (0010,0219) and Genetic Modifications Code Sequence (0010,0229) with a coding scheme of "MGI".

  • Another source of pre-coordinated codes for strains is the NCI Thesaurus, which includes a snapshot of strains from the International Mouse Strain Resource (IMSR), as children of (C14421, NCIt, "Inbred Mouse Strains"). See http://ncit.nci.nih.gov/ncitbrowser/pages/concept_details.jsf?dictionary=NCI_Thesaurus&code=C14421.

  • For example, a C57BL/6J mouse strain from The Jackson Laboratory might be identified as:

    • Strain Description (0010,0212) = "C57BL/6J"

    • Strain Nomenclature (0010,0213) = "MGI_2013"

    • Strain Code Sequence (0010,0219)

      • >Code Value (0008,0100) = "3028467"

      • >Coding Scheme Designator (0008,0102) = "MGI"

      • >Code Meaning (0008,0104) = "C57BL/6J"

    • Strain Stock Sequence (0010,0216)

      • >Strain Stock Number (0010,0214) = "000664"

      • >Strain Source (0010,0217) = "Jrep"

      • >Strain Source Registry Code Sequence (0010,0215)

        • >>Code Value (0008,0100) = 126850

        • >>Coding Scheme Designator (0008,0102) = "DCM"

        • >>Code Meaning (0008,0104) = "ILCR"

  • For example, a FVB/N mouse with a Tg(MMTV-Erbb2*)NDL2-5Mul transgene might be identified as:

    • Strain Description (0010,0212) = "FVB/N-Tg(MMTV-Erbb2*)NDL2-5Mul"

    • Strain Nomenclature (0010,0213) = "MGI_2013"

    • Genetic Modifications Sequence (0010,0221)

      • >Genetic Modifications Description (0010,0222) = "Tg(MMTV-Erbb2*)NDL2-5Mul"

      • >Genetic Modifications Nomenclature (0010,0223) = "MGI_2013"

      • >Genetic Modifications Code Sequence (0010,0229)

        • >>Code Value (0008,0100) = "3793949"

        • >>Coding Scheme Designator (0008,0102) = "MGI"

        • >>Code Meaning (0008,0104) = "Tg(MMTV-Erbb2*)NDL2-5Mul"

    In this example, a precoordinated code for the genetic modification is defined in MGI, but not for the mouse strain.